SCHEMBL2731300

SCHEMBL2731300

Fc1ccc2c(-c3c(F)c(F)c(F)c(F)c3F)c3c(F)ccc(F)c3c(-c3ccccc3)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2 P11137 1/20 0.37
MAP2K4 P45985 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
LMNA P02545 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAOB P27338 1/20 0.34
TNKS O95271 1/20 0.34
PTGS2 P35354 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
CCNE2 O96020 1/20 0.31
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31
CCNE1 P24864 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12086213 1.00 MAP2 (0.37) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL2728102 0.92 MAOB (0.36) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL12086110 0.90 MAP2 (0.38) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL2728484 0.90 MAP2 (0.38) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL12086225 0.89 TDP1 (0.35) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL2726493 0.89 TDP1 (0.35) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL2726479 0.88 CA3 (0.35) ALDH1A1CCNE2CDK4CCND1CCNE1
SCHEMBL2726487 0.88 DHODH (0.38) MAP2ALDH1A1PTGS2CYP1A2CYP2C9
SCHEMBL2728156 0.88 LMNA (0.40) MAP2MAP2K4TDP1CTDSP1LMNA
SCHEMBL2726578 0.87 CYP1A2 (0.41) MAP2TDP1LMNAHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 MAP2 886/4885MAP2K4 604/4885TDP1 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.