Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634630 | 0.79 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL14440405 | 0.75 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27894922 | 0.75 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25177265 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2HTT | |
| SCHEMBL28846178 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2HTT | |
| SCHEMBL29470610 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28737239 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL6658247 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6659880 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8282260 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031376-A | Pyrazolopyridine compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-03-01 | — | — | CN | disclosed |