Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18427393 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL40338 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL42485 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| E1501 SCHEMBL901210 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL10701155 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL7049526 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL9383761 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL7054415 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| E1501 SCHEMBL14031569 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 | |
| SCHEMBL21518223 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1SLC6A2SLC6A3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1326461-A | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2001-12-12 | — | — | CN | claimed |
| CN-105452244-A | Benzothiophene derivatives as estrogen receptor inhibitors | GLAXOSMITHKLINE IP DEV LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-104736569-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligase | UNIV YALE | 2015-06-24 | — | — | CN | disclosed |
| CN-102770421-B | Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions | ARISGEN SA | 2014-11-26 | — | — | CN | disclosed |
| CN-101684190-B | Composition for forming coating layer, metal pattern material and method for producing same | FUJI PHOTO FILM CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-101622243-B | Sulfonamide derivative | ASAHI KASEI PHARMA CORP | 2013-12-04 | — | — | CN | disclosed |
| CN-101754970-B | Macrocyclic indole derivatives for the treatment of hepatitis c infections | ANGELETTI P IST RICHERCHE BIO | 2013-07-10 | — | — | CN | disclosed |
| CN-102803223-A | Cyclic compound having substituted phenyl group | DAIICHI SANKYO CO LTD | 2012-11-28 | — | — | CN | disclosed |
| CN-102770421-A | Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions | ARISGEN SA | 2012-11-07 | — | — | CN | disclosed |
| CN-101801982-A | Macrocyclic indole derivatives for the treatment of hepatitis C infections | ANGELETTI P IST RICHERCHE BIO | 2010-08-11 | — | — | CN | disclosed |
| CN-101754970-A | The Macrocyclic indole derivatives that is used for the treatment of hepatitis C | ANGELETTI P IST RICHERCHE BIO | 2010-06-23 | — | — | CN | disclosed |
| CN-101684190-A | Composition for forming coating layer, metal pattern material and method for producing same | FUJIFILM CORP | 2010-03-31 | — | — | CN | disclosed |
| CN-101622243-A | Sulfonamide derivative | ASAHI KASEI PHARMA CORP | 2010-01-06 | — | — | CN | disclosed |
| CN-100441556-C | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL LTD (FI) | 2008-12-10 | — | — | CN | disclosed |
| CN-1861555-A | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL LTD (FI) | 2006-11-15 | — | — | CN | disclosed |
| CN-1263720-C | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL OY LTD (FI) | 2006-07-12 | — | — | CN | disclosed |
| CN-1399622-A | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL OY LTD (FI) | 2003-02-26 | — | — | CN | disclosed |
| CN-1030604-C | Heterocyclic compounds | GLAXO SPA (IT) | 1996-01-03 | — | — | CN | disclosed |
| CN-1064682-A | The preparation method of heterogeneous ring compound | GLAXO SPA (IT) | 1992-09-23 | — | — | CN | disclosed |