Sugi Predict

Sugi Predict / Compounds / SCHEMBL42485

SCHEMBL42485

SCHEMBL42485

CC(=S)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.63
▸ CA12 O43570 1/20 0.61
▸ CA1 P00915 1/20 0.61
▸ CA2 P00918 1/20 0.61
▸ CA9 Q16790 1/20 0.61
▸ TDP1 Q9NUW8 3/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ SLC6A2 P23975 1/20 0.50
▸ SLC6A3 Q01959 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ TSHR P16473 2/20 0.48
▸ LMNA P02545 2/20 0.46
▸ HCAR2 Q8TDS4 1/20 0.46
▸ IDO1 P14902 1/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162539 0.98 ALDH1A1 (0.61) ALDH1A1CA12CA1CA2CA9
SCHEMBL18427393 0.81 ALDH1A1 (0.68) ALDH1A1CA12CA1CA2CA9
SCHEMBL1722105 0.81 CA12 (0.65) ALDH1A1CA12CA1CA2CA9
SCHEMBL27313233 0.81 ALDH1A1 (0.68) ALDH1A1CA12CA1CA2CA9
SCHEMBL40338 0.81 ALDH1A1 (0.68) ALDH1A1CA12CA1CA2CA9
SCHEMBL28218969 0.81 CA12 (0.65) ALDH1A1CA12CA1CA2CA9
SCHEMBL672370 0.79 ALDH1A1 (0.55) ALDH1A1CA12CA1CA2CA9
SCHEMBL20249068 0.79 ALDH1A1 (0.66) ALDH1A1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL11753023 0.79 CA12 (0.63) ALDH1A1CA12CA1CA2CA9
SCHEMBL17104782 0.78 CA12 (0.57) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 — — CN claimed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 — — CN claimed
CN-108425104-A A kind of coating production using sulfhydryl compound as transition zone 江苏菲沃泰纳米科技有限公司 2018-08-21 — — CN claimed
CN-108060183-A A kind of lipase-catalyzed online synthesis 6-（Benzylthio）The method of -6- oxo vinyl caproates 浙江工业大学 2018-05-22 — — CN claimed
CN-108060184-A A kind of method of lipase-catalyzed online synthesis S- thioacetic acid benzyl esters 浙江工业大学 2018-05-22 — — CN claimed
CN-118638142-A Method for preparing acyl silane by using alkene under induction of visible light 南京理工大学 2024-09-13 — — CN disclosed
CN-113795499-B Process for producing alkoxysilyl group-containing thiocarboxylate 迈图高新材料公司 2024-03-19 — — CN disclosed
CN-111848321-B Chiral aminated sulfoxide and preparation method thereof 南方科技大学 2023-01-03 — — CN disclosed
CN-113795499-A Process for producing alkoxysilyl group-containing thiocarboxylic ester 迈图高新材料公司 2021-12-14 — — CN disclosed
US-11078157-B1 Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same UNIVERSITY OF OREGON (US) 2021-08-03 — — US disclosed
CN-108017522-B Preparation process of 2, 6-dibromobenzene methane sulfonyl chloride 贵州大学 2021-01-05 — — CN disclosed
CN-111848321-A Chiral aminated sulfoxide and preparation method thereof 南方科技大学 2020-10-30 — — CN disclosed
US-20040186293-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle JOHNSON PAUL D (US) 2004-09-23 — — US disclosed
US-20040176609-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle JOHNSON PAUL D (US) 2004-09-09 — — US disclosed
CN-1500813-A Polymerization with living characteristics ��Ļ���Ű˾ 2004-06-02 — — CN disclosed
CN-1137144-C Polymerization with living characteristics ��Ļ���Ű˾ 2004-02-04 — — CN disclosed
EP-1337530-A1 OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS Pharmacia & Upjohn Company (US) 2003-08-27 — — EP disclosed
US-20020133021-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle PHARMACIA & UPJOHN COMPANY 2002-09-19 — — US disclosed
WO-2002059115-A1 OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 2002-08-01 — — WO disclosed
CN-1228787-A Polymerization with living characteristics DU PONT (US) 1999-09-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133021-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 ALDH1A1 744/4885CA12 4434/4885CA1 4749/4885
US-20040186293-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 ALDH1A1 744/4885CA12 4434/4885CA1 4749/4885
US-20040176609-A1 Oxazolidinones having a benzannulated 6- or 7-membered heterocycle OXA1L, CDK16, MT-ND6 ALDH1A1 744/4885CA12 4434/4885CA1 4749/4885
US-11078157-B1 Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same CBS, SQOR, QSOX1 ALDH1A1 193/4885CA12 2245/4885CA1 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.