SCHEMBL27313293

SCHEMBL27313293

COc1ccc(C[CH]O)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
PPARG P37231 1/20 0.67
PPARD Q03181 1/20 0.67
PPARA Q07869 1/20 0.67
CA2 P00918 1/20 0.61
STAT3 P40763 1/20 0.54
KDM4E B2RXH2 2/20 0.53
ATM Q13315 2/20 0.53
PTGS1 P23219 2/20 0.53
CYP3A4 P08684 3/20 0.51
LDHA P00338 1/20 0.51
ALOX5 P09917 1/20 0.51
AR P10275 1/20 0.51
TRPM8 Q7Z2W7 1/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911904 0.83 ALDH1A1 (0.71) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL11911908 0.83 ALDH1A1 (0.71) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL557409 0.82 ALDH1A1 (0.69) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL15265592 0.82 ALDH1A1 (0.69) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL30644304 0.82 ALDH1A1 (0.69) ALDH1A1PPARGPPARDPPARACA2
Methyleugenol SCHEMBL1869396 0.80 ALDH1A1 (1.00) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL27420720 0.80 ALDH1A1 (0.67) ALDH1A1PPARGPPARDPPARACA2
Methyleugenol SCHEMBL113794 0.80 ALDH1A1 (1.00) ALDH1A1PPARGPPARDPPARACA2
Methyleugenol SCHEMBL29376951 0.80 ALDH1A1 (1.00) ALDH1A1PPARGPPARDPPARACA2
SCHEMBL3343652 0.80 ALDH1A1 (0.67) ALDH1A1PPARGPPARDPPARACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1030319-C 20- and 21-amino steroid EUPJOHN CORP (US) 1995-11-22 CN claimed
CN-86106226-A 20-and 21-amino steroids 1987-03-18 CN claimed
CN-1030319-C 20- and 21-amino steroid EUPJOHN CORP (US) 1995-11-22 CN disclosed
CN-86106226-A 20-and 21-amino steroids 1987-03-18 CN disclosed