Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | PPARD | Q03181 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644304 | 0.98 | ALDH1A1 (0.69) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL557409 | 0.98 | ALDH1A1 (0.69) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL20615143 | 0.85 | CALM1 (0.58) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL23375947 | 0.84 | ALDH1A1 (0.53) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL5978889 | 0.84 | ALDH1A1 (0.53) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL11911908 | 0.83 | ALDH1A1 (0.71) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL11911904 | 0.83 | ALDH1A1 (0.71) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL15174299 | 0.83 | ALDH1A1 (0.51) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL4775183 | 0.83 | MEN1 (0.53) | ALDH1A1PPARGPPARDPPARACA2 | |
| SCHEMBL195794 | 0.82 | ALDH1A1 (0.50) | ALDH1A1PPARGPPARDPPARACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586899-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2017-03-07 | — | — | US | disclosed |
| US-20150336887-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CORREVIO CANADA CORP. (CA) | 2015-11-26 | — | — | US | disclosed |
| US-9115081-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2015-08-25 | — | — | US | disclosed |
| US-20130102791-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2013-04-25 | — | — | US | disclosed |
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | disclosed |
| EP-1828099-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | Cardimone Pharma Corporation (CA) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006088525-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-08-24 | — | — | WO | disclosed |
| CN-1309959-A | Cosmetic or dermatological sunscreen preparation | BASF AG (DE) | 2001-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102791-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | ALDH1A1 3196/4885PPARG 1721/4885PPARD 1995/4885 |
| US-20150336887-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | ALDH1A1 3196/4885PPARG 1721/4885PPARD 1995/4885 |
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | ALDH1A1 3196/4885PPARG 1721/4885PPARD 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.