Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312078 | 0.88 | ASAH1 (0.57) | NOTUMASAH1TSHRRAB9AL3MBTL1 | |
| SCHEMBL20047281 | 0.87 | EGFR (0.50) | NOTUMASAH1TSHRRAB9AL3MBTL1 | |
| SCHEMBL27312101 | 0.86 | NPSR1 (0.54) | NOTUMASAH1RXFP1TSHRRAB9A | |
| SCHEMBL27312100 | 0.85 | IDO1 (0.56) | NOTUMRXFP1RAB9AL3MBTL1MAPT | |
| SCHEMBL27312082 | 0.84 | ASAH1 (0.45) | NOTUMASAH1TSHRRAB9AL3MBTL1 | |
| SCHEMBL27312355 | 0.82 | NOTUM (0.43) | NOTUMASAH1RXFP1TSHRRAB9A | |
| SCHEMBL2117436 | 0.82 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1MAPT | |
| SCHEMBL27312077 | 0.82 | ALDH1A1 (0.51) | ASAH1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL30877041 | 0.79 | HTR6 (0.45) | NOTUMASAH1KMT2ANPSR1 | |
| SCHEMBL27312619 | 0.79 | HTR6 (0.45) | NOTUMASAH1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091450-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-05-02 | — | — | WO | disclosed |