SCHEMBL27313655

SCHEMBL27313655

CCc1ccc(CNCc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.67
LMNA P02545 1/20 0.65
ALDH1A1 P00352 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
TDP1 Q9NUW8 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
BCHE P06276 1/20 0.53
POLB P06746 1/20 0.53
RAB9A P51151 1/20 0.53
MAOA P21397 1/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL7579450 0.98 TP53 (0.70) TP53LMNAALDH1A1NPSR1MEN1
SCHEMBL4396092 0.90 LMNA (0.77) TP53LMNAALDH1A1NPSR1MEN1
SCHEMBL10054993 0.87 MEN1 (0.74) MEN1KMT2ATDP1BCHEMAOA
SCHEMBL8251058 0.86 GAA (0.74) TP53ALDH1A1MEN1KMT2ATDP1
Ethylbenzene SCHEMBL27405402 0.84 TP53 (0.93) TP53ALDH1A1MEN1KMT2ASMN1; SMN2
Benzene SCHEMBL11697595 0.84 MEN1 (0.78) MEN1KMT2ATDP1BCHEMAOA
SCHEMBL1654 0.84 MEN1 (0.78) MEN1KMT2ATDP1BCHEMAOA
SCHEMBL5799878 0.84 MEN1 (0.78) MEN1KMT2ATDP1BCHEMAOA
Diethylamine SCHEMBL23466778 0.83 MEN1 (0.61) TP53MEN1KMT2ATDP1SMN1; SMN2
Alcohol SCHEMBL5555254 0.83 MEN1 (0.61) TP53LMNAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350180-A Industrial preparation method and application of high-purity alpha-aminonitrile 哈尔滨理工大学 2025-01-24 CN claimed
CN-119350180-A Industrial preparation method and application of high-purity alpha-aminonitrile 哈尔滨理工大学 2025-01-24 CN disclosed
WO-2024091450-A1 COMPOUNDS AND METHODS FOR TREATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-02 WO disclosed