SCHEMBL27314741

SCHEMBL27314741

CCCCCCCc1cc(O)ccc1C(=O)OC(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.49
HTT P42858 2/20 0.49
TYR P14679 2/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PTGS2 P35354 3/20 0.42
FAAH O00519 1/20 0.42
KDM4E B2RXH2 1/20 0.41
PPARA Q07869 1/20 0.41
CNR1 P21554 5/20 0.41
CNR2 P34972 4/20 0.41
PTGES O14684 1/20 0.40
TOP2A P11388 1/20 0.40
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8602515 0.99 ALOX5 (0.47) ALOX5HTTTYRMEN1TP53
SCHEMBL127366 0.82 CA12 (0.59) ALOX5HTTTYRMEN1TP53
SCHEMBL29288325 0.82 CA12 (0.54) ALOX5HTTTYRMEN1TP53
SCHEMBL25393746 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL29062899 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL130709 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL28450761 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL5317593 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL29285270 0.81 TSHR (0.57) ALOX5HTTTYRMEN1TP53
SCHEMBL4366300 0.79 PPARA (0.59) ALOX5HTTTYRMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1028750-C Method for preparing carboxylic ester compound MITSUI PETROCHEMICAL IND (JP) 1995-06-07 CN disclosed
CN-1066866-A Carbonate and the liquid-crystal composition and the liquid crystal cells thereof that contain described compound MITSUI PETROCHEMICAL IND (JP) 1992-12-09 CN disclosed
CN-1054094-A Carboxylate compound, liquid crystal composition containing the same, and liquid crystal cell using the same MITSUI PETROCHEMICAL IND (JP) 1991-08-28 CN disclosed