Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 5/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | PRKX | P51817 | 1/20 | 0.48 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.48 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.48 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532730 | 0.84 | MAOA (0.65) | MAOBMAOAAKT1ROCK2PIM1 | |
| SCHEMBL8512404 | 0.83 | MAOB (0.56) | MAOBMAOACYP1A2ALOX5PDGFRB | |
| SCHEMBL5987640 | 0.82 | MAOB (0.56) | MAOBMAOALCKCYP1A2CYP1A1 | |
| SCHEMBL13307888 | 0.80 | AKT1 (0.50) | MAOBMAOAAKT1ROCK2PIM1 | |
| SCHEMBL13308164 | 0.79 | ALDH1A1 (0.55) | MAOBMAOAAKT1ROCK2PIM1 | |
| SCHEMBL2265668 | 0.79 | MAOB (0.71) | MAOBMAOALCKCCNB2CDK1 | |
| SCHEMBL2187050 | 0.79 | ALDH1A1 (0.69) | AKT1ROCK2PIM1PRKACARPS6KB1 | |
| SCHEMBL2187055 | 0.79 | ALDH1A1 (0.69) | AKT1ROCK2PIM1PRKACARPS6KB1 | |
| SCHEMBL27473841 | 0.78 | MAPK1 (0.49) | MAOBMAOACYP1A2ALOX5PDGFRB | |
| SCHEMBL6666536 | 0.77 | AKT1 (0.48) | MAOBMAOAAKT1ROCK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091542-A1 | COMPOUNDS AND COMPOSITIONS AS GPR52 MODULATORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-05-02 | — | — | WO | disclosed |