Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.57 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.53 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.51 |
| ▸ | RET | P07949 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 7/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315059 | 0.86 | NTRK1 (0.56) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL12537191 | 0.84 | NTRK1 (0.42) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL13869025 | 0.82 | NTRK1 (0.50) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL12537587 | 0.80 | NTRK1 (0.73) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL12537650 | 0.80 | NTRK1 (0.58) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL14651915 | 0.79 | NTRK1 (0.38) | NTRK1NTRK2ACVRL1CSNK2A2CSNK2A1 | |
| SCHEMBL12283438 | 0.79 | NTRK1 (0.38) | NTRK1NTRK2ACVRL1CSNK2A2CSNK2A1 | |
| SCHEMBL14488780 | 0.78 | ACVRL1 (0.52) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL26690322 | 0.78 | ACVRL1 (0.52) | NTRK1NTRK2ACVRL1RETKDR | |
| SCHEMBL15932552 | 0.78 | ACVRL1 (0.52) | NTRK1NTRK2ACVRL1RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4611900-A1 | RET-LDD PROTEIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024097980-A1 | RET-LDD PROTEIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |