Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27302892 | 0.76 | FEN1 (0.43) | MTNR1AMTNR1B | |
| SCHEMBL12228580 | 0.68 | MAP2 (0.46) | MAP2CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL16065345 | 0.67 | PDE3B (0.38) | ERN1CYP1A2CYP2C9CYP2C19MET | |
| SCHEMBL23000274 | 0.65 | MAP2 (0.40) | MAP2CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL21884849 | 0.65 | AR (0.36) | MAP2ERN1NPSR1MET | |
| SCHEMBL28424735 | 0.65 | KDM4E (0.49) | MAP2 | |
| SCHEMBL5324128 | 0.64 | BRD4 (0.36) | ERN1RXFP1 | |
| SCHEMBL2462946 | 0.64 | KDM4E (0.51) | CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8371524 | 0.61 | RXFP1 (0.54) | MAP2PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12255399 | 0.61 | EGFR (0.39) | MTNR1AMTNR1BCYP1A2CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031222-A | β-(fluorine methylene radical)-5-hydroxytryptophan and derivative as the monoamine oxidase prodrugs for inhibition | MERRELL DOW PHARMA (US) | 1989-02-22 | — | — | CN | claimed |