Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832660 | 0.78 | ADRB2 (0.46) | BRD4BRPF1CREBBPGAAMAPT | |
| SCHEMBL17447389 | 0.76 | TTR (0.37) | ERN1NR4A2GAAMAPTKDM4E | |
| SCHEMBL16065345 | 0.76 | PDE3B (0.38) | ERN1HTR1DHTR2AHTR2CHTR7 | |
| SCHEMBL21884849 | 0.73 | AR (0.36) | ERN1GAAMAPTMEN1KMT2A | |
| SCHEMBL15546942 | 0.72 | PKM (0.39) | NR4A2GAAMAPTPKMRXFP1 | |
| SCHEMBL2462946 | 0.71 | KDM4E (0.51) | GAAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL12255399 | 0.70 | EGFR (0.39) | EGFRGAAMAPTRXFP1KDM4E | |
| SCHEMBL7832691 | 0.70 | GAA (0.61) | EGFRSRCNR4A2GAAMAPT | |
| SCHEMBL14487045 | 0.67 | EGFR (0.67) | EGFRSRCNR4A2GAAMAPT | |
| SCHEMBL30608287 | 0.67 | EGFR (0.67) | EGFRSRCNR4A2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109783-A2 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | WO | disclosed |