Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 17/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27315191 | 0.76 | RET (0.51) | NTRK1NTRK2RET | |
| SCHEMBL27315205 | 0.76 | NTRK1 (0.54) | NTRK1NTRK2RET | |
| SCHEMBL27315615 | 0.76 | NTRK1 (0.58) | NTRK1NTRK2RET | |
| SCHEMBL27315617 | 0.74 | NTRK1 (0.43) | NTRK1NTRK2RET | |
| SCHEMBL27315219 | 0.74 | RET (0.54) | NTRK1NTRK2RET | |
| SCHEMBL27315613 | 0.70 | RET (0.50) | RET | |
| SCHEMBL27394822 | 0.66 | RET (0.57) | RET | |
| SCHEMBL27315227 | 0.66 | NTRK1 (0.55) | NTRK1NTRK2RET | |
| SCHEMBL27315170 | 0.65 | NTRK1 (0.57) | NTRK1NTRK2RET | |
| SCHEMBL27315176 | 0.65 | NTRK1 (0.55) | NTRK1NTRK2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097980-A1 | RET-LDD PROTEIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |