Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938122 | 0.88 | AR (0.55) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL27315641 | 0.86 | AR (0.62) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL727424 | 0.81 | RAB9A (0.54) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL18674683 | 0.79 | AR (0.64) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL22263324 | 0.79 | AR (0.66) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL30938129 | 0.79 | AR (0.66) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL26458261 | 0.78 | AR (0.67) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL1473981 | 0.77 | AR (0.71) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL18674648 | 0.75 | RAB9A (0.74) | ARRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL24939664 | 0.74 | AR (0.60) | ARRAB9ANPC1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102810-A1 | BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR | MONTELINO THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | WO | disclosed |