Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731177 | 0.84 | MAPK8 (0.44) | ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL2730721 | 0.81 | RECQL (0.49) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL30462688 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EPOLBL3MBTL1ATM | |
| SCHEMBL29387787 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EPOLBL3MBTL1ATM | |
| SCHEMBL39208 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4EPOLBL3MBTL1ATM | |
| SCHEMBL29744440 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL28791262 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL21594507 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL7678729 | 0.71 | PLA2G2A (0.51) | FOLH1ALDH1A1KDM4EKMT2ACCR2 | |
| SCHEMBL28165405 | 0.71 | KMT2A (0.53) | FOLH1ALDH1A1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-A1 | INDOLE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059776-A1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2012-05-10 | — | — | WO | disclosed |