Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731333 | 0.74 | HDAC6 (0.41) | FOLH1MAPK8HDAC6KMT2AALDH1A1 | |
| SCHEMBL2731764 | 0.74 | EGFR (0.37) | PLA2G2AFOLH1KDM4EL3MBTL1MAPK8 | |
| SCHEMBL2730314 | 0.73 | CCR2 (0.41) | PLA2G2AFOLH1MAPK8CCR2MAPK9 | |
| SCHEMBL17456645 | 0.72 | PTGDR2 (0.52) | PLA2G2AKDM4EATML3MBTL1HDAC6 | |
| Hydrochloric Acid SCHEMBL2731134 | 0.72 | CCR2 (0.41) | FOLH1L3MBTL1MAPK8CCR2MAPK9 | |
| SCHEMBL17199972 | 0.72 | MAPK8 (0.46) | PLA2G2AKDM4EMAPK8CCR2MAPK9 | |
| SCHEMBL27981508 | 0.72 | KDM4E (0.58) | PLA2G2AKDM4EATML3MBTL1OGG1 | |
| SCHEMBL2731589 | 0.71 | FOLH1 (0.46) | FOLH1KDM4EATML3MBTL1CCR2 | |
| Hydrochloric Acid SCHEMBL2732706 | 0.71 | MAPK8 (0.45) | PLA2G2AKDM4EMAPK8CCR2MAPK9 | |
| SCHEMBL27688347 | 0.70 | PLA2G2A (0.54) | PLA2G2AKDM4EATML3MBTL1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091148-A1 | 3-substituted indole antiproliferative angiogenesis inhibitors | ABBOTT LABORATORIES | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091148-A1 | 3-substituted indole antiproliferative angiogenesis inhibitors | MKI67, FLT4, IDO1 | PLA2G2A 3293/4885FOLH1 1971/4885KDM4E 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.