Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24732304 | 0.73 | DYRK1A (0.51) | DYRK1AAURKATTKAURKBINCENP | |
| SCHEMBL24037298 | 0.71 | ALDH1A1 (0.43) | DYRK1AALDH1A1HPGDMAPTLMNA | |
| SCHEMBL26066981 | 0.70 | PIK3CD (0.38) | AURKAAURKBINCENPPIK3CDPIK3CA | |
| SCHEMBL19832066 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HPGDMAPTLMNAGAA | |
| SCHEMBL17540831 | 0.69 | MAPT (0.44) | DYRK1AALDH1A1HPGDMAPTLMNA | |
| SCHEMBL19531807 | 0.69 | DYRK1A (0.43) | DYRK1AAURKATTKAURKBINCENP | |
| SCHEMBL12919977 | 0.68 | GPR55 (0.50) | AURKBPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL15044974 | 0.68 | GPR55 (0.43) | AURKATTKAURKBINCENPMAPT | |
| SCHEMBL13086621 | 0.68 | MKNK1 (0.49) | DYRK1AAURKATTKAURKBINCENP | |
| SCHEMBL17806578 | 0.68 | KCNH2 (0.46) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |