Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 11/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.42 |
| ▸ | KDR | P35968 | 10/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 9/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27316811 | 0.87 | KIT (0.41) | PDK2FGFR3FGFR1KDRFGFR2 | |
| SCHEMBL26833884 | 0.85 | BRD4 (0.42) | FGFR3FGFR1KDRFGFR2FGFR4 | |
| SCHEMBL27316819 | 0.79 | PDK2 (0.51) | PDK2FGFR3FGFR1FGFR2FGFR4 | |
| SCHEMBL17809818 | 0.78 | ERN1 (0.45) | KDRERN1LOXL2 | |
| SCHEMBL27316812 | 0.77 | MKNK1 (0.42) | FGFR3FGFR1KDRFGFR2ERN1 | |
| SCHEMBL10359827 | 0.74 | TP53 (0.59) | TP53ALOX15 | |
| SCHEMBL17795636 | 0.73 | ERN1 (0.47) | ERN1LOXL2 | |
| SCHEMBL12671453 | 0.73 | LOXL2 (0.42) | FGFR3FGFR1KDRFGFR2FGFR4 | |
| SCHEMBL17809820 | 0.70 | LOXL2 (0.44) | PDK2FGFR3KDRFLT3ERN1 | |
| SCHEMBL17806536 | 0.68 | RXRA (0.43) | PDK2KDRERN1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |