Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.86 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.71 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22469940 | 0.92 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL23001307 | 0.92 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL29365020 | 0.92 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL22469941 | 0.92 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL28687393 | 0.85 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL28687390 | 0.85 | NLRP3 (1.00) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL25144914 | 0.82 | NLRP3 (1.00) | NLRP3PTPN1MEN1KMT2ACFTR | |
| SCHEMBL14220547 | 0.79 | PTPN1 (0.74) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL20339998 | 0.77 | NLRP3 (0.81) | NLRP3PTPN1DUSP22MEN1KMT2A | |
| SCHEMBL20340001 | 0.77 | NLRP3 (0.81) | NLRP3PTPN1DUSP22MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023232752-A1 | PREVENTION OR MITIGATION OF T-CELL ENGAGING AGENT-RELATED ADVERSE EFFECTS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-07 | — | — | WO | disclosed |