Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867200 | 1.00 | NQO1 (0.48) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL30867136 | 0.89 | NQO1 (0.48) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL27318685 | 0.89 | NQO1 (0.48) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL30867152 | 0.85 | SSTR2 (0.39) | NQO1NPC1RAB9ACCNT1CCNA2 | |
| SCHEMBL27319084 | 0.85 | SSTR2 (0.39) | NQO1NPC1RAB9ACCNT1CCNA2 | |
| SCHEMBL30867175 | 0.84 | NQO1 (0.46) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL27318674 | 0.84 | NQO1 (0.46) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL30867197 | 0.83 | GBA1 (0.69) | NPC1RAB9AGBA1CCNT1CCNA2 | |
| SCHEMBL30867186 | 0.83 | GBA1 (0.55) | NQO1NPC1RAB9AGBA1CCNT1 | |
| SCHEMBL27319390 | 0.83 | GBA1 (0.55) | NQO1NPC1RAB9AGBA1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |