Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NEK4 | P51957 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867152 | 1.00 | SSTR2 (0.39) | SSTR2SSTR4HTR1ANQO1GSK3B | |
| SCHEMBL27318958 | 0.89 | HTR1A (0.39) | SSTR2SSTR4HTR1ANQO1GSK3B | |
| SCHEMBL31534082 | 0.89 | HTR1A (0.39) | SSTR2SSTR4HTR1ANQO1GSK3B | |
| SCHEMBL30867200 | 0.85 | NQO1 (0.48) | HTR1ANQO1CLK4CCNT1CCNA2 | |
| SCHEMBL27318924 | 0.85 | NQO1 (0.48) | HTR1ANQO1CLK4CCNT1CCNA2 | |
| SCHEMBL30867125 | 0.84 | MAPT (0.38) | SSTR2SSTR4HTR1ANQO1GSK3B | |
| SCHEMBL27318948 | 0.84 | MAPT (0.38) | SSTR2SSTR4HTR1ANQO1GSK3B | |
| SCHEMBL31534056 | 0.82 | GBA1 (0.41) | SSTR2SSTR4HTR1AGSK3BNEK4 | |
| SCHEMBL31534073 | 0.81 | CDK4 (0.43) | SSTR2SSTR4HTR1AGSK3BPRKCI | |
| SCHEMBL27319565 | 0.81 | CDK4 (0.43) | SSTR2SSTR4HTR1AGSK3BPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076300-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2024-04-11 | — | — | WO | disclosed |