Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313002 | 0.81 | CNR2 (0.42) | MAPTTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL28279760 | 0.68 | HSD17B10 (0.54) | RAB9AMAPTTDP1MEN1KMT2A | |
| SCHEMBL2603317 | 0.67 | PIK3C3 (0.41) | MEN1KMT2AALDH1A1PIK3C3 | |
| SCHEMBL22213815 | 0.67 | PIK3C3 (0.41) | MEN1KMT2AALDH1A1PIK3C3 | |
| SCHEMBL18913836 | 0.67 | PIK3C3 (0.41) | MEN1KMT2AALDH1A1PIK3C3 | |
| SCHEMBL9035188 | 0.66 | CYP19A1 (0.46) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7518980 | 0.65 | SIRT3 (0.39) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27323298 | 0.65 | TSHR (0.47) | MAPTKDM4EALOX15SMN1; SMN2PIK3C3 | |
| SCHEMBL27555215 | 0.64 | MTNR1A (0.63) | RAB9AMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL4105231 | 0.63 | PIK3C3 (0.43) | KDM4EALDH1A1HSD17B10PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |