Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27320122 | 0.81 | RAB9A (0.45) | ALOX15MEN1KMT2AMAPTTDP1 | |
| SCHEMBL29643357 | 0.72 | HSP90AA1 (0.42) | MEN1KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL28279760 | 0.70 | HSD17B10 (0.54) | LMNAMMP8MEN1KMT2AMAPT | |
| SCHEMBL4296695 | 0.70 | DRD2 (0.43) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL18784918 | 0.70 | DRD2 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13041188 | 0.63 | BACE1 (0.53) | MEN1KMT2A | |
| SCHEMBL28119493 | 0.62 | CYP2D6 (0.50) | ITGA4MEN1KMT2AITGB7ALDH1A1 | |
| SCHEMBL9516925 | 0.62 | LMNA (0.68) | LMNAALOX15MMP8MEN1KMT2A | |
| SCHEMBL7280926 | 0.62 | LMNA (0.68) | LMNAALOX15MMP8MEN1KMT2A | |
| SCHEMBL9516205 | 0.62 | KMT2A (0.50) | LMNAMMP8MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |