SCHEMBL27320155

SCHEMBL27320155

CC(I)c1ccc2cc(O)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
HSD17B10 Q99714 2/20 0.45
CYP2C9 P11712 2/20 0.45
UGT2B7 P16662 1/20 0.44
ESR1 P03372 8/20 0.43
ESR2 Q92731 8/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
ABL1 P00519 2/20 0.41
ABCB1 P08183 2/20 0.41
BCR P11274 2/20 0.41
CYP2D6 P10635 1/20 0.39
HSD17B1 P14061 1/20 0.39
CYP2B6 P20813 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20398782 0.83 CYP1A2 (0.50) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL487450 0.83 CYP1A2 (0.56) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL15853505 0.81 UGT2B7 (0.67) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL9118979 0.81 UGT2B7 (0.67) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL13586940 0.79 CYP1A2 (0.46) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL13706061 0.79 CYP1A2 (0.46) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL18772356 0.79 CYP2C9 (0.53) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL13557419 0.78 UGT2B7 (0.63) CYP1A2UGT2B7TSHRHIF1ATDP1
SCHEMBL12356631 0.78 ESR1 (0.50) CYP1A2HSD17B10CYP2C9UGT2B7ESR1
SCHEMBL27323386 0.77 HSD17B10 (0.44) CYP1A2HSD17B10CYP2C9UGT2B7ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112123-A1 NOVEL COMPOUND AS SELECTIVE ESTROGEN RECEPTOR MODULATOR 재단법인 대구경북첨단의료산업진흥재단 2024-05-30 WO disclosed