Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 7/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12356631 | 0.95 | ESR1 (0.50) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| SCHEMBL20398782 | 0.86 | CYP1A2 (0.50) | CYP1A2UGT2B7HSD17B10CYP2C9HIF1A | |
| Hydrogen Peroxide SCHEMBL9172508 | 0.85 | UGT2B7 (0.60) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| Hydrogen Peroxide SCHEMBL9840257 | 0.85 | UGT2B7 (0.60) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| SCHEMBL30031337 | 0.85 | UGT2B7 (0.58) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| SCHEMBL181347 | 0.85 | UGT2B7 (0.58) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| SCHEMBL15853505 | 0.84 | UGT2B7 (0.67) | CYP1A2UGT2B7HSD17B10CYP2C9HIF1A | |
| SCHEMBL9118979 | 0.84 | UGT2B7 (0.67) | CYP1A2UGT2B7HSD17B10CYP2C9HIF1A | |
| Water SCHEMBL10391367 | 0.83 | UGT2B7 (0.56) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C | |
| Water SCHEMBL9862280 | 0.83 | UGT2B7 (0.56) | CYP1A2UGT2B7TRPA1PTGS1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286902-A | Process for preparation of 2-(6-methoxy-2-naphthyl)propionic acid and intermediates therefor utilizing 2,6-diisopropylnaphthalene | KOCH INDUSTRIES, INC. (US) | 1994-02-15 | — | — | US | claimed |
| US-5041634-A | Process for the preparation of carboxylated aromatic hydroxy compounds | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | claimed |
| EP-0320452-A2 | Process for preparing carboxylated aromatic hydroxy derivatives | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |
| JP-3227948-A | — | — | None | — | — | JP | disclosed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230244147-A1 | COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-03 | — | — | US | disclosed |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | TRINEURO (KR) | 2023-07-06 | — | — | US | disclosed |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | TRINEURO (KR) | 2023-07-06 | — | — | US | disclosed |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230161251-A1 | COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| US-5003113-A | Process of producing isopropylnaphthols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| US-4996372-A | In a basic aqueous solution, then acid cleaving in the presence of hydrogen peroxide | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0370729-A1 | Process for producing isopropylnaphthols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4929771-A | Process for the preparation of alkyl-substituted phenols or naphthols | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4906790-A | Method of oxidizing secondary alkyl substituted naphtalenes and a process of producing isopropylnaphthols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0320451-A2 | Process for preparing alkyl-substituted phenols or naphthols | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |
| EP-0320452-A2 | Process for preparing carboxylated aromatic hydroxy derivatives | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |
| EP-0308133-A1 | A method of oxidising secondary alkyl substituted naphthalenes | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| EP-0239643-A1 | PROCESS FOR OXIDIZING 2,6-DIISOPROPYLNAPHTHALENE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230161251-A1 | COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM | PYM1, OR10J3, C5 | CYP1A2 1933/4885UGT2B7 4692/4885TRPA1 1953/4885 |
| US-20230244147-A1 | COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM | OR10J3, PYM1, AP1M1 | CYP1A2 833/4885UGT2B7 4124/4885TRPA1 2461/4885 |
| US-20230167081-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | IKZF1, IKZF3, IKZF2 | CYP1A2 2512/4885UGT2B7 3977/4885TRPA1 4704/4885 |
| US-20230212144-A1 | 5-MEMBERED HETEROARYL DERIVATIVE CONTAINING AT LEAST ONE N, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDERS, CONTAINING SAME AS ACTIVE INGREDIENT | HTR5A, HTR2C, TPH1 | CYP1A2 336/4885UGT2B7 653/4885TRPA1 4522/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | CYP1A2 4271/4885UGT2B7 3970/4885TRPA1 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.