Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15853505 | 1.00 | UGT2B7 (0.67) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL5610446 | 0.89 | UGT2B7 (0.82) | UGT2B7CYP1A2CYP2C9TSHRHIF1A | |
| SCHEMBL20398782 | 0.84 | CYP1A2 (0.50) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL487450 | 0.84 | CYP1A2 (0.56) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL10268972 | 0.82 | CYP1A2 (0.52) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL27320155 | 0.81 | CYP1A2 (0.46) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL13706061 | 0.81 | CYP1A2 (0.46) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL13586940 | 0.81 | CYP1A2 (0.46) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL12356631 | 0.80 | ESR1 (0.50) | UGT2B7CYP1A2HSD17B10CYP2C9ESR1 | |
| SCHEMBL110360 | 0.80 | UGT2B7 (1.00) | UGT2B7CYP1A2CYP3A4TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398288-B1 | Process for preparing optically active 2-arylalkanoic acids, in particular 2-arylpropionic acids | PUETTER MEDICE CHEM PHARM (DE) | 1995-10-18 | — | — | EP | disclosed |
| US-5380927-A | Process for preparing optically active 2-aryl-alkanoic acids, in particular 2-aryl-propionic acids | MEDICE CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1995-01-10 | — | — | US | disclosed |
| US-5266723-A | Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids | MEDICE, LTD., CHEM.-PHARM. FABRIK PUTTER GMBH & CO. KG (DE) | 1993-11-30 | — | — | US | disclosed |
| CN-1050373-A | Preparation optically-active 2-aryl-alkanoic, the particularly method of 2-arylpropionic acid | PUETTER MEDICE CHEM PHARM (DE) | 1991-04-03 | — | — | CN | disclosed |