Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311008 | 0.89 | MTNR1A (0.42) | MTNR1AMTNR1BKMT2ANR1H2NR1H3 | |
| SCHEMBL27320350 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BKMT2ACNR2 | |
| SCHEMBL27311007 | 0.73 | MTNR1A (0.50) | MTNR1AMTNR1BKMT2ACNR2 | |
| SCHEMBL7881984 | 0.73 | ALDH1A1 (0.50) | MTNR1AMTNR1BKMT2ACNR2 | |
| SCHEMBL11687003 | 0.73 | KMT2A (0.45) | MTNR1AMTNR1BKMT2ANR1H2NR1H3 | |
| SCHEMBL7943776 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL18537881 | 0.71 | NR1H2 (0.53) | MTNR1AMTNR1BNR1H2NR1H3 | |
| SCHEMBL19410240 | 0.68 | KMT2A (0.52) | MTNR1AMTNR1BKMT2ANR1H2CNR2 | |
| SCHEMBL28812065 | 0.68 | MTNR1A (0.50) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL7879892 | 0.68 | MTNR1A (0.69) | MTNR1AMTNR1BKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067988-C | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICS K K (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1051301-C | Indoloylguanidine derivatives | SUMITOMO PHARMA (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1136038-A | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICS K K (JP) | 1996-11-20 | — | — | CN | disclosed |
| CN-1106800-A | Indoloylguanidine derivatives | SUMITOMO PHARMA (JP) | 1995-08-16 | — | — | CN | disclosed |