Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27319542 | 0.81 | KLKB1 (0.44) | — | |
| SCHEMBL27317866 | 0.81 | KLKB1 (0.44) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27337079 | 0.78 | KLKB1 (0.48) | BCHEACHEALDH1A1 | |
| SCHEMBL27415918 | 0.78 | HPGD (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27335851 | 0.76 | KMT2A (0.38) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27419335 | 0.74 | KLKB1 (0.44) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL27323388 | 0.74 | NPC1 (0.50) | PDK1ALDH1A1 | |
| SCHEMBL27507480 | 0.72 | EPHX2 (0.73) | BCHEACHERORCALDH1A1KMT2A | |
| SCHEMBL27401020 | 0.72 | PPARG (0.50) | ALDH1A1 | |
| SCHEMBL27321553 | 0.71 | KLKB1 (0.46) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046268-C | Indolin-2-one derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-11-10 | — | — | CN | disclosed |
| CN-1117727-A | Indolin-2-one derivative | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1996-02-28 | — | — | CN | disclosed |