Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27351179 | 0.79 | HTT (0.41) | — | |
| SCHEMBL27765306 | 0.79 | HTT (0.41) | — | |
| SCHEMBL27605600 | 0.78 | NAPRT (0.44) | POLB | |
| SCHEMBL27786734 | 0.77 | POLB (0.66) | POLB | |
| SCHEMBL27624613 | 0.75 | HCAR2 (0.41) | — | |
| SCHEMBL27576356 | 0.72 | POLB (0.44) | POLB | |
| SCHEMBL27275148 | 0.72 | ALDH1A1 (0.41) | POLBRECQL | |
| SCHEMBL28198796 | 0.72 | ALDH1A1 (0.41) | POLBRECQL | |
| SCHEMBL2634209 | 0.71 | CYP3A4 (0.57) | — | |
| SCHEMBL27764938 | 0.70 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047776-C | Pharmacologically active pyridine derivatives and processes for the preparation thereof | NOVARTIS AG (CH) | 1999-12-29 | — | — | CN | disclosed |
| CN-1115982-A | pyridine derivatives having pharmacological activity and preparation method thereof | CIBA GEIGY AG (CH) | 1996-01-31 | — | — | CN | disclosed |