Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1794480 | 0.83 | PARP1 (0.56) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL674193 | 0.81 | PARP1 (0.54) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL24738862 | 0.79 | PARP1 (0.52) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL1361076 | 0.79 | PARP1 (0.52) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL1196056 | 0.79 | PARP1 (0.69) | PARP1HTTERCC5FEN1ALDH1A1 | |
| SCHEMBL8160941 | 0.79 | PARP1 (0.52) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL13221751 | 0.77 | PARP1 (0.55) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL7763955 | 0.77 | PARP1 (0.50) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL4088684 | 0.77 | PARP1 (0.60) | PARP1TSHRHTTERCC5FEN1 | |
| SCHEMBL9055041 | 0.76 | PARP1 (0.48) | PARP1TSHRHTTERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047277-A | 2,3-dihydro-1,3-indene-dione derivative and contain the herbicidal composition of this material as active ingredient | MITSUBISHI CHEM IND (JP) | 1990-11-28 | — | — | CN | disclosed |