Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604413 | 0.83 | PARP1 (0.48) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL21783054 | 0.82 | PARP1 (0.47) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL2015776 | 0.82 | MAOA (0.48) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL2662195 | 0.80 | PARP1 (0.46) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL11225682 | 0.79 | PARP1 (0.44) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL20247744 | 0.79 | MAOA (0.46) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL17868848 | 0.79 | PARP1 (0.44) | PARP1MAOAMAOBERCC5FEN1 | |
| SCHEMBL1794480 | 0.78 | PARP1 (0.56) | PARP1ERCC5FEN1GRIN2BHTT | |
| SCHEMBL9845816 | 0.78 | PARP1 (0.47) | PARP1HTTMAPTHPGDRAB9A | |
| SCHEMBL9843296 | 0.78 | CES2 (0.50) | PARP1MAOAMAOBGRIN2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484535-B | Method for preparing indanthrone | 河北科技大学 | 2021-08-10 | — | — | CN | claimed |
| JP-5125000-A | — | — | None | — | — | JP | disclosed |
| JP-5320088-A | — | — | None | — | — | JP | disclosed |
| CN-108484535-B | Method for preparing indanthrone | 河北科技大学 | 2021-08-10 | — | — | CN | disclosed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-1505155-B1 | CARBONYL REDUCTASE, GENE THEREOF AND USE OF THE SAME | KANEKA CORP (JP) | 2008-12-03 | — | — | EP | disclosed |
| EP-0562361-B1 | Indane-1, 3-dione derivatives and herbicides containing them as active ingredient | MITSUBISHI CHEM CORP (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5369085-A | Effective against grasses in agricultural crops | MITSUBISHI KASEI CORPORATION (JP) | 1994-11-29 | — | — | US | disclosed |
| JP-H05320088-A | INDAN-1, 3-DIONE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORP | 1993-12-03 | — | — | JP | disclosed |
| EP-0562361-A1 | Indane-1, 3-dione derivatives and herbicides containing them as active ingredient | Mitsubishi Chemical Corporation (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0398258-B1 | INDAN-1,3-DIONE DERIVATIVE AND HERBICIDAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1993-08-04 | — | — | EP | disclosed |
| JP-H05125000-A | METHOD FOR PRODUCING ALPHA-CHLOROMETHLSTYRENE DERIVATIVE | MITSUBISHI KASEI CORP | 1993-05-21 | — | — | JP | disclosed |
| US-5110342-A | INDAN-1,3-DIONE DERIVATIVE AND HERBICIDAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1992-05-05 | — | — | US | disclosed |
| US-5076830-A | INDAN-1,3-DIONE DERIVATIVE AND HERBICIDAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0398258-A1 | Indan-1,3-dione derivative and herbicidal composition containing the same as active ingredient | MITSUBISHI KASEI CORPORATION (JP) | 1990-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | PARP1 4724/4885MAOA 2664/4885MAOB 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.