Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243196 | 0.74 | UGT2B17 (0.47) | ALDH1A1UGT2B17MAPTLTB4RLTB4R2 | |
| SCHEMBL1736688 | 0.72 | UGT2B17 (0.41) | UGT2B17 | |
| SCHEMBL2929777 | 0.72 | UGT2B17 (0.41) | UGT2B17 | |
| Hydrochloric Acid SCHEMBL27423140 | 0.71 | KDM1A (0.47) | NOS1NOS2LTB4RLTB4R2 | |
| SCHEMBL28120719 | 0.71 | AADAT (0.36) | NOS1NOS2GAAMAPTLTB4R | |
| Hydrochloric Acid SCHEMBL27320632 | 0.69 | KCNH2 (0.46) | — | |
| SCHEMBL22919236 | 0.65 | MAOB (0.44) | LTB4RLTB4R2 | |
| SCHEMBL7863226 | 0.65 | MAOB (0.44) | LTB4RLTB4R2 | |
| SCHEMBL10327336 | 0.64 | KMT2A (0.43) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL7250487 | 0.64 | CYP19A1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047859-A | Benzo cycloalkane derivatives and preparation method thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-12-19 | — | — | CN | disclosed |