SCHEMBL7243196

SCHEMBL7243196

Cc1cc(C)c2c(c1)C(O)C(Cc1ccccc1)CC2

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
UGT2B17 O75795 2/20 0.47
LTB4R Q15722 11/20 0.42
LTB4R2 Q9NPC1 11/20 0.42
MAPT P10636 1/20 0.35
GBA1 P04062 1/20 0.35
ALDH1A1 P00352 1/20 0.34
STS P08842 1/20 0.34
HSD17B1 P14061 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7242871 0.80 EBP (0.41) UGT2B17
SCHEMBL27322693 0.74 MEN1 (0.38) UGT2B17LTB4RLTB4R2MAPTALDH1A1
SCHEMBL7245450 0.74 NPC1 (0.36) UGT2B17LTB4RLTB4R2MAPT
SCHEMBL31558350 0.72 LTB4R (0.53) LTB4RLTB4R2GBA1
SCHEMBL7241734 0.70 HTR6 (0.46) LTB4RLTB4R2
Hydrochloric Acid SCHEMBL10446805 0.70 EBP (0.44) UGT2B17MAPT
SCHEMBL7249674 0.70 BLM (0.41) LTB4RLTB4R2GBA1ALDH1A1
SCHEMBL7251512 0.69 ACHE (0.51)
SCHEMBL1508636 0.69 UGT2B17 (0.82) UGT2B17
SCHEMBL7250487 0.69 CYP19A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191279-A1 Urea derivatives useful as anticancer agents GOLDSTEIN STEVEN WAYNE (US) 2003-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191279-A1 Urea derivatives useful as anticancer agents CCNA1, CCNE1, CCND1 UGT2B17 552/4885LTB4R 3845/4885LTB4R2 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.