Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884735 | 0.94 | SIGMAR1 (0.52) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL28543867 | 0.84 | SIGMAR1 (0.57) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL4772258 | 0.80 | SIGMAR1 (0.61) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL2257602 | 0.79 | SIGMAR1 (0.59) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL6749797 | 0.78 | SIGMAR1 (0.49) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL2452523 | 0.77 | SIGMAR1 (0.57) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL8380136 | 0.77 | SIGMAR1 (0.57) | SIGMAR1HRH3MC4RDRD4LMNA | |
| SCHEMBL2144916 | 0.77 | SIGMAR1 (0.68) | SIGMAR1MC4RDRD4LMNAPOLB | |
| SCHEMBL3505735 | 0.76 | SIGMAR1 (0.55) | SIGMAR1HRH3MC4RLMNACYP3A4 | |
| SCHEMBL7380692 | 0.76 | SIGMAR1 (0.55) | SIGMAR1HRH3MC4RDRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046278-C | Azolylamine derivative | KAKEN PHARMA CO LTD (JP) | 1999-11-10 | — | — | CN | disclosed |
| CN-1122598-A | Azolylamine derivative | KAKEN PHARMA CO LTD (JP) | 1996-05-15 | — | — | CN | disclosed |