Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501875 | 0.91 | HRH3 (0.40) | HRH3KCNH2CYP2D6 | |
| SCHEMBL25480233 | 0.91 | HRH3 (0.44) | HRH3KCNH2CYP2D6 | |
| SCHEMBL25569155 | 0.90 | NCF1 (0.42) | HRH3 | |
| SCHEMBL12890856 | 0.89 | HRH3 (0.43) | HRH3KCNH2CYP2D6 | |
| SCHEMBL23594654 | 0.85 | HRH3 (0.33) | HRH3 | |
| SCHEMBL24671761 | 0.83 | NCF1 (0.46) | HRH3KCNH2 | |
| SCHEMBL8364993 | 0.83 | HRH3 (0.40) | HRH3KCNH2CYP2D6 | |
| SCHEMBL23134084 | 0.81 | HRH3 (0.42) | HRH3KCNH2 | |
| SCHEMBL16565633 | 0.80 | HRH3 (0.38) | HRH3KCNH2 | |
| SCHEMBL2737395 | 0.80 | HRH3 (0.38) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244918-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |