Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671761 | 0.90 | NCF1 (0.46) | NCF1HRH3ACHESLC6A4HRH4 | |
| SCHEMBL27323580 | 0.90 | HRH3 (0.40) | HRH3 | |
| SCHEMBL24501875 | 0.82 | HRH3 (0.40) | HRH3 | |
| SCHEMBL25565871 | 0.81 | NCF1 (0.54) | NCF1HRH3ACHESLC6A4HRH4 | |
| SCHEMBL22859167 | 0.81 | NCF1 (0.54) | NCF1HRH3ACHESLC6A4HRH4 | |
| SCHEMBL25480233 | 0.81 | HRH3 (0.44) | NCF1HRH3 | |
| SCHEMBL25566048 | 0.81 | NCF1 (0.54) | NCF1HRH3ACHESLC6A4HRH4 | |
| SCHEMBL23594654 | 0.80 | HRH3 (0.33) | HRH3 | |
| SCHEMBL12890856 | 0.79 | HRH3 (0.43) | HRH3 | |
| SCHEMBL757866 | 0.78 | NCF1 (0.62) | NCF1HRH3ACHEHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |