Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27324272 | 0.96 | SLC34A1 (0.43) | SLC34A1CA1CA2ALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL2226319 | 0.91 | CA1 (0.40) | SLC34A1CA1CA2ALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL5104735 | 0.91 | — | — | |
| Phosphoric Acid SCHEMBL27486017 | 0.87 | — | — | |
| Phosphoric Acid SCHEMBL28320521 | 0.83 | CA1 (0.42) | SLC34A1CA1CA2ALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL4978568 | 0.77 | — | — | |
| Phosphoric Acid SCHEMBL25166911 | 0.76 | CA2 (0.50) | SLC34A1CA2ALDH1A1TSHRTDP1 | |
| Phosphoric Acid SCHEMBL2811672 | 0.76 | CA2 (0.50) | SLC34A1CA2ALDH1A1TSHRTDP1 | |
| Phosphoric Acid SCHEMBL8711577 | 0.76 | SLC34A1 (0.60) | SLC34A1CA2ALDH1A1TSHRTDP1 | |
| Phosphoric Acid SCHEMBL21293873 | 0.76 | CA2 (0.50) | SLC34A1CA2ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036398-C | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1997-11-12 | — | — | CN | disclosed |
| CN-1077199-A | THERAPEUTIC NUCLEOSIDES | WELLCOME FOUND (GB) | 1993-10-13 | — | — | CN | disclosed |