Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1270225 | 0.99 | GPR119 (0.54) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL27975342 | 0.91 | GPR119 (0.54) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| Iodide SCHEMBL1270227 | 0.90 | GPR119 (0.55) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL3144261 | 0.84 | GPR119 (0.60) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL12897372 | 0.83 | GPR119 (0.54) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL907209 | 0.82 | GPR119 (0.58) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL1269323 | 0.82 | GPR119 (0.58) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL30926236 | 0.81 | GPR119 (0.58) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL12440438 | 0.81 | GPR119 (0.58) | GPR119SMN1; SMN2THRBGAAF2RL3 | |
| SCHEMBL12897357 | 0.80 | GPR119 (0.51) | GPR119SMN1; SMN2THRBGAAF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-04-11 | — | — | US | disclosed |
| EP-2445907-A1 | THIAZOLYLPIPERIDINE DERIVATES AS FUNGICIDES | Bayer Cropscience AG (DE) | 2012-05-02 | — | — | EP | disclosed |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| WO-2010149275-A1 | THIAZOLYLPIPERIDINE DERIVATES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090476-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GPR119 428/4885SMN1; SMN2 4486/4885THRB 702/4885 |
| US-20130090477-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GPR119 428/4885SMN1; SMN2 4486/4885THRB 702/4885 |
| US-20110046178-A1 | Thiazolylpiperidine Derivatives as Fungicides | NAT1, GRHPR, PTPRG | GPR119 428/4885SMN1; SMN2 4486/4885THRB 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.