Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.76 |
| ▸ | CA2 | P00918 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941399 | 0.76 | CA1 (0.56) | CA1CA2LMNASMN1; SMN2MEN1 | |
| SCHEMBL7222183 | 0.74 | CA1 (0.64) | CA1CA2LMNASMN1; SMN2MEN1 | |
| SCHEMBL10388931 | 0.73 | POLB (0.65) | CA1CA2LMNASMN1; SMN2MEN1 | |
| SCHEMBL3981403 | 0.72 | LMNA (0.56) | CA1CA2LMNASMN1; SMN2MEN1 | |
| SCHEMBL7451017 | 0.70 | POLB (0.73) | CA1CA2LMNASMN1; SMN2MEN1 | |
| Bicarbonate SCHEMBL9638235 | 0.70 | FFAR1 (0.71) | LMNACYP1A2MAOB | |
| SCHEMBL9126144 | 0.69 | MAOB (0.90) | LMNASMN1; SMN2L3MBTL1MAOB | |
| SCHEMBL20876895 | 0.69 | NR4A2 (0.51) | CA1CA2LMNACYP1A2RAB9A | |
| SCHEMBL2727830 | 0.69 | NR4A2 (0.51) | CA1CA2LMNACYP1A2RAB9A | |
| SCHEMBL2713179 | 0.69 | NR4A2 (0.51) | CA1CA2LMNACYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035054-C | Novel isoxazolines as antiinflammatory agents | PFIZER (US) | 1997-06-04 | — | — | CN | disclosed |
| CN-1091132-A | New De isoxazolines as antiinflammatory agents | PFIZER (US) | 1994-08-24 | — | — | CN | disclosed |