Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222190 | 0.87 | LMNA (0.65) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL4799264 | 0.87 | ALDH1A1 (0.62) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL7893785 | 0.84 | ALDH1A1 (0.58) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL4797835 | 0.82 | MEN1 (0.56) | LMNAKMT2AMEN1ALDH1A1MAPK10 | |
| SCHEMBL4799530 | 0.82 | ALDH1A1 (0.63) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL4799279 | 0.82 | ALDH1A1 (0.63) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL4799265 | 0.82 | ALDH1A1 (0.63) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL7893788 | 0.82 | ALDH1A1 (0.58) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL4800211 | 0.82 | ALDH1A1 (0.65) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL7890173 | 0.81 | ALDH1A1 (0.62) | CA1CA2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583141-B1 | T cell mediated rheumatic diseases | JANSSEN PHARMACEUTICA, N.V. (BE) | 2003-06-24 | — | — | US | disclosed |