Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 12/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.61 |
| ▸ | PDE4A | P27815 | 2/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453218 | 0.88 | ADORA2B (0.72) | ADORA2BADORA2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL516014 | 0.87 | ADORA2B (0.72) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL10354149 | 0.85 | ADORA2B (0.68) | ADORA2BLMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL11610641 | 0.85 | PDE4A (0.58) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL31482443 | 0.83 | ADORA2B (0.81) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL4384952 | 0.83 | ADORA2B (0.78) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL11702145 | 0.82 | ADORA2B (0.78) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL11701929 | 0.82 | ADORA2B (0.78) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL11699832 | 0.82 | ADORA2B (0.78) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL10394216 | 0.82 | ADORA2B (0.78) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032939-A | PROCESS FOR PRODUCING CHAMICAL PHARMACENTICAL | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1989-05-17 | — | — | CN | disclosed |