SCHEMBL27325877

SCHEMBL27325877

CN1CCC[C@H]1CC(=O)ON

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 4/20 0.43
CHRNA4 P43681 4/20 0.43
CHRNA7 P36544 3/20 0.43
CHRNA5 P30532 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13662774 1.00 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL4088784 0.84 CHRNB2 (0.44) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL4088779 0.84 CHRNB2 (0.44) CHRNB2CHRNA4CHRNA7CHRNA5
Hydrochloric Acid SCHEMBL21801537 0.82 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL1033553 0.79 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL336170 0.79 CHRNB2 (0.45) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL336171 0.79 CHRNB2 (0.45) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL24872393 0.79 CYP1A2 (0.44) CHRNB2CHRNA4CHRNA7CHRNA5
Hydrochloric Acid SCHEMBL2673741 0.78 CHRNB2 (0.42) CHRNB2CHRNA4CHRNA7CHRNA5
SCHEMBL13740779 0.77 CHRNB2 (0.47) CHRNB2CHRNA4CHRNA7CHRNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097355-A1 DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS VICINITAS THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed