Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 5/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834689 | 0.83 | HTR1A (0.56) | HTR1AHTR2CHTR1DHTR1BTBXAS1 | |
| SCHEMBL27287897 | 0.82 | HTR1D (0.53) | HTR1AHTR2CHTR1DHTR1BCYP19A1 | |
| SCHEMBL27343955 | 0.81 | HTR1A (0.53) | HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL27308222 | 0.80 | HTR1D (0.42) | HTR1AHTR1DHTR1BCYP19A1 | |
| SCHEMBL8783976 | 0.80 | HTR1A (0.53) | HTR1AHTR2CHTR1DHTR1BTBXAS1 | |
| SCHEMBL27328403 | 0.72 | NOTUM (0.36) | HTR1AHTR1DHTR1B | |
| SCHEMBL27343954 | 0.71 | HTR1A (0.50) | HTR1AHTR2CHTR1DHTR1BCYP19A1 | |
| SCHEMBL6945754 | 0.70 | HTR1A (0.79) | HTR1AHTR2CHTR1DHTR1BTBXAS1 | |
| SCHEMBL27328413 | 0.70 | HTR1D (0.47) | HTR1AHTR1DHTR1B | |
| SCHEMBL7480332 | 0.69 | HTR2C (0.73) | HTR1AHTR2CHTR1DHTR1BTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060479-C | Preparation method for imidazole derivatives | MERCK SHARP & DOHME (GB) | 2001-01-10 | — | — | CN | claimed |
| CN-1161967-A | Preparation method for imidazole derivatives | MERCK SHARP & DOHME (GB) | 1997-10-15 | — | — | CN | claimed |
| CN-1061654-C | Tetrazole derivatives and process for preparation thereof | MERCK SHARP & DOHME (GB) | 2001-02-07 | — | — | CN | disclosed |
| CN-1060479-C | Preparation method for imidazole derivatives | MERCK SHARP & DOHME (GB) | 2001-01-10 | — | — | CN | disclosed |
| CN-1038681-C | Triazole derivatives and their use as fungicides | MERCK SHARP DOHME LTD (GB) | 1998-06-10 | — | — | CN | disclosed |
| CN-1161967-A | Preparation method for imidazole derivatives | MERCK SHARP & DOHME (GB) | 1997-10-15 | — | — | CN | disclosed |
| CN-1157821-A | Process for preparation of tetrazole derivatives | MERCK SHARP & DOHME (DE) | 1997-08-27 | — | — | CN | disclosed |