Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795601 | 1.00 | PRKCA (0.65) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL5493689 | 1.00 | PRKCA (0.65) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL1008410 | 1.00 | PRKCA (0.65) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL7411764 | 1.00 | PRKCA (0.65) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL1009136 | 1.00 | PRKCA (0.65) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL9436412 | 0.98 | PRKCA (0.62) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL4324597 | 0.93 | PRKCA (0.59) | PRKCAUSP2ADRA1DPTAFRHTR1D | |
| SCHEMBL4912502 | 0.91 | PRKCA (0.62) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL4912512 | 0.91 | PRKCA (0.62) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL1000470 | 0.91 | PRKCA (0.62) | PRKCAPRKCEPRKCQPRKCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006492-A | — | — | None | — | — | JP | disclosed |
| JP-2006493-A | — | — | None | — | — | JP | disclosed |
| US-11479802-B2 | Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family | REGENERON PHARMACEUTICALS, INC. (US) | 2022-10-25 | — | — | US | disclosed |
| EP-3610029-A1 | ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY | Regeneron Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018190970-A1 | ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY | REGENERON PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| US-20180291422-A1 | Assays For Screening Activity Of Modulators Of Members Of The Hydroxysteroid (17-Beta) Dehydrogenase (HSD17B) Family | REGENERON PHARMACEUTICALS, INC. | 2018-10-11 | — | — | US | disclosed |
| CN-105441385-A | Effective method for generating animal and embryonic stem cells of reprogramming differentiation cells and reprogramming cells | ADVANCED CELL TECH INC | 2016-03-30 | — | — | CN | disclosed |
| CN-103827075-B | The preparation method of 1-palmityl-3-ethanoyl glycerine and use it to prepare the method for 1-palmityl-2-sub-oleoyl-3-ethanoyl glycerine | ENZYCHEM LIFESCIENCES CORP. (KR) | 2015-09-16 | — | — | CN | disclosed |
| CN-103827075-A | Preparation method of 1-palmitoyl-3-acetylglycerol, and preparation method of 1-palmitoyl-2-linoleoyl-3-acetylglycerol using same | ENZYCHEM LIFESCIENCES CORP | 2014-05-28 | — | — | CN | disclosed |
| US-7906147-B2 | superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography | NANOPROBES, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080089836-A1 | superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography | NANOPROBES, INC. (US) | 2008-04-17 | — | — | US | disclosed |
| US-6562804-B2 | For stimulating hair growth in a mammal | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20020172657-A1 | Hair-growing agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-11-21 | — | — | US | disclosed |
| EP-1232740-A2 | Hair-growing agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-08-21 | — | — | EP | disclosed |
| EP-0284395-B1 | NOVEL GLYCEROL DERIVATIVE AND ANTI-HYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-5183811-A | Glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| US-4962096-A | WITH REDUCED PLATELET AGGREGATING ACTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| JP-H026492-A | NOVEL GLYCEROL DERIVATIVE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME DERIVATIVE | NIPPON CHEMIPHAR CO LTD | 1990-01-10 | — | — | JP | disclosed |
| JP-H026493-A | NOVEL GLYCEROL DERIVATIVE, ITS PRODUCTION AND HYPOTENSOR CONTAINING THE SAME DERIVATIVE | NIPPON CHEMIPHAR CO LTD | 1990-01-10 | — | — | JP | disclosed |
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020172657-A1 | Hair-growing agent | PHOSPHO1, PLD1, SGMS1 | PRKCA 2499/4885USP2 2204/4885ADRA1D 2888/4885 |
| US-20080089836-A1 | superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography | TFRC, FABP1, SCARB1 | PRKCA 2358/4885USP2 1613/4885ADRA1D 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.