Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300303 | 0.85 | TAAR1 (0.60) | TAAR1IDO1AGXTDAOCYP17A1 | |
| SCHEMBL15456313 | 0.84 | TAAR1 (0.57) | TAAR1IDO1AGXTDAOMIF | |
| SCHEMBL3298408 | 0.83 | CALM1 (0.57) | TAAR1IDO1AGXTDAOCYP17A1 | |
| SCHEMBL7929350 | 0.81 | TAAR1 (0.52) | TAAR1IDO1AGXTDAOCYP17A1 | |
| SCHEMBL3026516 | 0.81 | TAAR1 (0.53) | TAAR1IDO1AGXTDAOSLC6A3 | |
| SCHEMBL27693023 | 0.77 | PTPN5 (0.53) | TAAR1AGXTCYP17A1CYP3A4CYP11B1 | |
| SCHEMBL3032997 | 0.76 | IDO1 (0.44) | TAAR1IDO1AGXTDAOCYP3A4 | |
| SCHEMBL2414844 | 0.76 | TAAR1 (0.47) | TAAR1IDO1DAOMAOB | |
| SCHEMBL1501342 | 0.76 | CYP11B1 (0.69) | TAAR1IDO1AGXTDAOCYP17A1 | |
| SCHEMBL3022914 | 0.76 | PNMT (0.50) | TAAR1IDO1AGXTDAOCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009197-B | Process for preparing N, 3-disubstituted 2-oxindole-1-carboxamides | PFIZER (US) | 1990-08-15 | — | — | CN | disclosed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | disclosed |