SCHEMBL27329088

SCHEMBL27329088

C=CCOC(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 1/20 0.38
CYP3A4 P08684 1/20 0.35
NPC1 O15118 1/20 0.34
ADAM17 P78536 1/20 0.34
ALOX15 P16050 1/20 0.34
ALDH1A1 P00352 4/20 0.33
PTPRC P08575 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CCR5 P51681 1/20 0.32
HDAC2 Q92769 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725647 0.79 CYP3A4 (0.43) GSRMEN1KMT2ACYP2C19CYP3A4
SCHEMBL7691385 0.77 GSR (0.42) GSRMEN1KMT2ANPC1ADAM17
SCHEMBL435152 0.77 GSR (0.42) GSRMEN1KMT2ANPC1ADAM17
SCHEMBL7117064 0.75 GSR (0.40) GSRMEN1KMT2ACYP2C19CYP3A4
SCHEMBL376375 0.74 GSR (0.44) GSRMEN1KMT2ACYP2C19CYP3A4
SCHEMBL11129656 0.72 MEN1 (0.46) MEN1KMT2ACYP2C19SMN1; SMN2KDM4E
SCHEMBL2028620 0.72 GSR (0.43) GSRKMT2ANPC1ADAM17ALDH1A1
SCHEMBL3093470 0.72 MEN1 (0.46) MEN1KMT2ACYP2C19CYP3A4ALOX15
SCHEMBL7594456 0.72 GSR (0.38) GSRMEN1KMT2ACYP2C19SMN1; SMN2
SCHEMBL2184991 0.72 GSR (0.40) GSRMEN1KMT2ANPC1ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997147-B Synthesis and use of N-alkyl amino benzene alkyl ether 深圳市广昌达石油添加剂有限公司 2020-12-22 CN claimed
CN-1003042-B PROCESS FOR SYNTHESIS OF NITRO-PHENYL ALKYL ETHER 华东化工学院 1989-01-11 CN claimed
CN-1003042-B PROCESS FOR SYNTHESIS OF NITRO-PHENYL ALKYL ETHER 华东化工学院 1989-01-11 CN disclosed