SCHEMBL27329102

SCHEMBL27329102

O=C(O)C(CCCOc1ccccc1Cl)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PKM P14618 1/20 0.55
TDP1 Q9NUW8 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 2/20 0.49
TP53 P04637 2/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
HTT P42858 1/20 0.49
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49
DRD3 P35462 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
MAPT P10636 1/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 3/20 0.47
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607010 0.81 SLC1A5 (0.53) MEN1KMT2APKMSMN1; SMN2HPGD
SCHEMBL5080191 0.81 SLC1A5 (0.53) MEN1KMT2APKMSMN1; SMN2HPGD
SCHEMBL27288427 0.80 KDM4E (0.56) MEN1KMT2ATDP1L3MBTL1PPARG
SCHEMBL3161189 0.79 MEN1 (0.58) MEN1KMT2APKMTDP1SMN1; SMN2
SCHEMBL3168428 0.78 MEN1 (0.57) MEN1KMT2APKMTDP1SMN1; SMN2
SCHEMBL578719 0.77 LMNA (0.64) MEN1KMT2APKMTDP1SMN1; SMN2
SCHEMBL5523873 0.77 TDP1 (0.70) MEN1KMT2APKMTDP1HPGD
SCHEMBL9322243 0.77 MEN1 (0.55) MEN1KMT2APKMTDP1SMN1; SMN2
SCHEMBL9623483 0.76 MEN1 (0.46) MEN1KMT2APKMTDP1SMN1; SMN2
SCHEMBL3551990 0.76 MEN1 (0.63) MEN1KMT2APKMTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1007063-B COPOLYESTER VENO FINE CHEMICAL IND LTD (JP) 1990-03-07 CN disclosed
CN-86105004-A COPOLYESTER 1987-02-18 CN disclosed