SCHEMBL578719

SCHEMBL578719

O=C(O)CCOc1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
PKM P14618 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.54
HPGD P15428 3/20 0.53
TP53 P04637 2/20 0.53
RXRA P19793 1/20 0.53
RXRB P28702 1/20 0.53
HTT P42858 1/20 0.53
CXCL8 P10145 1/20 0.51
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.49
MITF O75030 1/20 0.49
XBP1 P17861 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
DRD2 P14416 1/20 0.49
DRD4 P21917 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3161189 0.91 MEN1 (0.58) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL3168428 0.89 MEN1 (0.57) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL9322243 0.88 MEN1 (0.55) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL9860833 0.87 MEN1 (0.58) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL1694563 0.86 LMNA (0.56) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL11488532 0.84 MEN1 (0.58) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL9001338 0.83 MEN1 (0.54) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL31107962 0.83 LMNA (0.53) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL21156896 0.83 LMNA (0.53) LMNAMEN1KMT2APKMSMN1; SMN2
SCHEMBL101520 0.81 PTGDR2 (0.68) MEN1KMT2ASMN1; SMN2HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102438450-A fruit thinning agent TAMINCO NV 2012-05-02 CN claimed
US-20120088668-A1 THINNING AGENT TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2012-04-12 US claimed
EP-2416649-A2 THINNING AGENT Taminco, Naamloze Venootschap (BE) 2012-02-15 EP claimed
WO-2010116256-A2 THINNING AGENT TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2010-10-14 WO claimed
US-20260144795-A1 SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS H. LUNDBECK A/S (DK) 2026-05-28 US disclosed
CN-106061267-B Application of chemical agent in stone fruit flower thinning 精细农用化学品有限公司 2022-02-01 CN disclosed
EP-3091836-B1 USE OF A CHEMICAL AGENT FOR THINNING OF STONE FRUIT FINE AGROCHEMICALS LTD (GB) 2020-05-27 EP disclosed
EP-3636807-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME Chugai Seiyaku Kabushiki Kaisha (JP) 2020-04-15 EP disclosed
US-20160330961-A1 USE OF A CHEMICAL AGENT FOR THINNING OF STONE FRUIT FINE AGROCHEMICALS LIMITED (GB) 2016-11-17 US disclosed
EP-3091836-A1 USE OF A CHEMICAL AGENT FOR THINNING OF STONE FRUIT Fine Agrochemicals Limited (GB) 2016-11-16 EP disclosed
WO-2015104344-A1 USE OF A CHEMICAL AGENT FOR THINNING OF STONE FRUIT FINE AGROCHEMICALS LIMITED (GB) 2015-07-16 WO disclosed
EP-2893809-A1 Use of a chemical agent for thinning of stone fruit Fine Agrochemicals Limited (GB) 2015-07-15 EP disclosed
WO-2011070131-A1 5-AMINO- 4-HYDROXYPENTOYL AMIDES TIBOTEC PHARMACEUTICALS (IE) 2011-06-16 WO disclosed
WO-2010116256-A2 THINNING AGENT TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) 2010-10-14 WO disclosed
US-20100062970-A1 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS EMISPHERE TECHNOLOGIES INC. (US) 2010-03-11 US disclosed
US-20100062970-A1 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS EMISPHERE TECHNOLOGIES INC. (US) 2010-03-11 US disclosed
US-20100062970-A1 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS EMISPHERE TECHNOLOGIES INC. (US) 2010-03-11 US disclosed
EP-2053918-A2 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS Emisphere Technologies, Inc. (US) 2009-05-06 EP disclosed
WO-2008022242-A2 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-02-21 WO disclosed
EP-0087858-A1 New chromanone compounds and pharmaceutical compositions containing them NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062970-A1 SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS EPX, HPD, CYP2C8 LMNA 2327/4885MEN1 3039/4885KMT2A 2202/4885
US-20260144795-A1 SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS HCRTR2, HCRTR1, CRHR1 LMNA 1231/4885MEN1 2106/4885KMT2A 2095/4885
US-20120088668-A1 THINNING AGENT NAT1, MAP2, AANAT LMNA 1560/4885MEN1 3321/4885KMT2A 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.