Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329949 | 0.96 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL27329950 | 0.96 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL889183 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12120074 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12792293 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12120077 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL889262 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12120073 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12792363 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA | |
| SCHEMBL12120081 | 0.93 | NAAA (0.58) | DGKADNM1NAAAHTR2CTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119098-A1 | LIPID NANOPARTICLE (LNP) DELIVERY SYSTEMS AND FORMULATIONS | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |